About Us…

The PRIMED+ (Psychosis Risk Immune Multimodal Early Detection Plus) research group is particularly interested in how environmental biological measures can help identify individuals who are at increased risk for developing psychosis, and early outcomes after psychosis has occurred. These are findings that can be translated into targeted interventions. The group investigate the association and causal mechanisms between increased innate inflammation and psychosis, developing a clinical model of psychosis and informed immune-related phenotyping.

Our research adopts a multidisciplinary approach, utilising advances in medicine, neuroscience, genetics, biosciences and data-driven analysis to better understand mental illness. This includes cutting-edge quantitative skills in computational modelling, statistical analysis, and data analytics using machine learning and other artificial intelligence-based techniques. The lab is led by Professor Rachel Upthegrove and Dr Jack Rogers and is based at the Institute for Mental Health, University of Birmingham.