2022
Journal Articles
Review Articles
Dunleavy, C, Elsworthy, RJ, Upthegrove, R, Wood, SJ & Aldred, S 2022, 'Inflammation in first-episode psychosis: The contribution of inflammatory biomarkers to the emergence of negative symptoms, a systematic review and meta-analysis', Acta Psychiatrica Scandinavica, 146(1), 6-20
Durdurak, BB, Upthegrove, R, Altaweel, N, Marwaha, S (2022) Understanding the Developmental Pathways and Onset of Bipolar Disorder and Borderline Personality Disorder in Young People: A Systematic Review of Reviews, BJPsych Open, 8(S1), S50-S50.
Durdurak, B, Marwaha, S, Upthegrove, R & Altaweel, N 2022, 'Understanding the development of bipolar disorder and borderline personality disorder in young people: a meta-review of systematic reviews', Psychological Medicine.
Maidment, I, Wong, G, Duddy, C, Upthegrove, R, Oduola, S, Allen, K, Jacklin, S, Howe, J & Macphee, M 2022, 'Medication optimisation in severe mental illness (MEDIATE): protocol for a realist review', BMJ open, vol. 12, no. 1, e058524.
Maidment, ID, Wong, G, Duddy, C, Upthegrove, R, Oduola, S, Robotham, D, Higgs, S, Ahern, A & Birdi, G 2022, 'REalist Synthesis Of non-pharmacologicaL interVEntions for antipsychotic-induced weight gain (RESOLVE) in people living with severe mental illness (SMI)', Systematic Reviews, vol. 11, no. 1, 42.
Shields, GE, Buck, D, Varese, F, Yung, AR, Thompson, A, Husain, N, Broome, MR, Upthegrove, R, Byrne, R & Davies, LM 2022, 'A review of economic evaluations of health care for people at risk of psychosis and for first-episode psychosis', BMC Psychiatry, vol. 22, no. 1, 126
Perry, BI, Vandenberghe, F, Garrido-Torres, N, Osimo, EF, Piras, M, Vazquez-Bourgon, J, Upthegrove, R, Grosu, C, Ortiz-Garcia De La Foz, V, Jones, PB, Laaboub, N, Ruiz-Veguilla, M, Stochl, J, Dubath, C, Canal-Rivero, M, Mallikarjun, P, Reymond-Delacrétaz, A, Ansermot, N, Fernandez-Egea, E, Crettol, S, Gamma, F, Plessen, KJ, Conus, P, Khandaker, GM, Murray, GK, Eap, CB, Crespo-Facorro, B. 2022, The psychosis metabolic risk calculator (PsyMetRiC) for young people with psychosis: International external validation and site-specific recalibration in two independent European samples. The Lancet Regional Health, 22, 2666-7762
Watson, AJ, Giordano, A, Suckling, J, Barnes, TRE, Husain, N, Jones, PB, Krynicki, CR, Lawrie, SM, Lewis, S, Nikkheslat, N, Pariante, CM, Upthegrove, R, Deakin, B, Dazzan, P & Joyce, EM 2022, 'Cognitive function in early-phase schizophrenia-spectrum disorder: IQ subtypes, brain volume and immune markers', Psychological Medicine.
Jones, R, Upthegrove, R, Price, M, Pritchard, M, Chandan, J, Legge , S & MacCabe, J 2022, 'Duration of prior psychotic illness and clozapine response: a retrospective observational study using electronic health records', Therapeutic advances in psychopharmacology, vol. 12, pp. 1-12.
Perry, BI, Bowker, N, Burgess, S, Wareham, NJ, Upthegrove, R, Jones, P, Khandaker, GM & Langenberg, C 2022, 'Evidence for shared genetic aetiology between schizophrenia, cardiometabolic and inflammation related traits: genetic correlation and colocalization analyses', Schizophrenia Bulletin Open, vol. 3, no. 1, sgac001.
Williams JA, Burgess S, Suckling J, et al. PIMS collaboration 2022, 'Inflammation and brain structure in schizophrenia and other neuropsychiatric disorders: A Mendelian randomization study', JAMA psychiatry, vol. 2022, pp. 1-11.
Villemonteix, T., Rogers, J.C., Courbet, O. et al. (2022) Sex matters: association between callous-unemotional traits and uncinate fasciculus microstructure in youths with conduct disorder. Brain Imaging and Behaviour 16, 263–269
PRONIA Consortium, Lalousis, PA, Schmaal, L, Wood, S, Reniers, R, Barnes, N, Chisholm, K, Griffiths, L, Stainton, A, Wen, J, Hwang, G, Davatzikos, C, Wenzel, J, Kambeitz-Ilankovic, L, Andreou, C, Bonivento, C, Dannlowski, U, Ferro, A, Liechtenstein, T, Riecher-Rössler, A, Romer, G, Rosen, M, Bertolino, A, Borgwardt, S, Brambilla, P, Kambeitz, J, Lencer, R, Pantelis, C, Ruhrmann, S, Salokangas, RKR, Schultze-Lutter, F, Schmidt, A, Meisenzahl, EM, Koutsouleris, N, Dwyer, D & Upthegrove, R 2022, 'Neurobiologically based stratification of recent onset depression and psychosis: identification of two distinct transdiagnostic phenotypes', Biological Psychiatry.
the PRONIA consortium 2022, 'Relationships between global functioning and neuropsychological predictors in subjects at high risk of psychosis or with a recent onset of depression', World Journal of Biological Psychiatry, 20, 1-9
PRONIA Consortium. Dwyer DB, Buciuman M, Ruef A, et al (2022) Clinical, Brain, and Multilevel Clustering in Early Psychosis and Affective Stages. JAMA Psychiatry; 79(7):677–689
Antonucci, LA, Penzel, N, Sanfelici, R, Pigoni, A, Kambeitz-Ilankovic, L, Dwyer, D, Ruef, A, Sen Dong, M, Öztürk, ÖF, Haidl, T, Rosen, M, Ferro, A, Pergola, G, Andriola, I, Blasi, G, Ruhrmann, S, Schultze-Lutter, F, Falkai, P, Kambeitz, J, Lencer, R, Dannlowski, U, Upthegrove, R, Salokangas, RKR, Pantelis, C, Meisenzahl, E, Wood, SJ, Brambilla, P, Borgwardt, S, Bertolino, A & Koutsouleris, N 2022, 'Using combined environmental-clinical classification models to predict role functioning outcome in clinical high-risk states for psychosis and recent-onset depression', British Journal of Psychiatry, vol. 220, no. 4, pp. 229–245.
Penzel, N, Antonucci, LA, Betz, LT, Sanfelici, R, Weiske, J, Pogarell, O, Cumming, P, Quednow, BB, Howes, O, Falkai, P, Upthegrove, R, Bertolino, A, Borgwardt, S, Brambilla, P, Lencer, R, Meisenzahl, E, Rosen, M, Haidl, T, Kambeitz-Ilankovic, L, Ruhrmann, S, Salokangas, RRK, Pantelis, C, Wood, SJ, Koutsouleris, N, Kambeitz, J & PRONIA Consortium 2021, 'Association between age of cannabis initiation and gray matter covariance networks in recent onset psychosis', Neuropsychopharmacology, vol. 2021, no. 00, pp. 1-10.
Watson, A., Giordano, A., Suckling, J., Barnes, T., Husain, N., Jones, P., . . . Joyce, E. (2022). Cognitive function in early-phase schizophrenia-spectrum disorder: IQ subtypes, brain volume and immune markers. Psychological Medicine, 1-10.
van Velzen LS, Dauvermann MR, Colic L, Villa LM, Savage HS, Toenders YJ, et al., (2022) Structural brain alterations associated with suicidal thoughts and behaviors in young people: results from 21 international studies from the ENIGMA Suicidal Thoughts and Behaviours consortium. Mol Psychiatry. Online ahead of print. PMID: 36071108
Nabulsi L, Farrell J, McPhilemy G, Kilmartin L, Dauvermann MR, Akudjedu TN, Najt P, Ambati S, Martyn FM, McLoughlin J, Gill M, Meaney J, Morris D, Frodl T, McDonald C, Hallahan B, Cannon DM.Neuropsychopharmacology. (2022) Normalization of impaired emotion inhibition in bipolar disorder mediated by cholinergic neurotransmission in the cingulate cortex. 47(9):1643-1651. Epub 2022 Jan 19.PMID: 35046509 Free PMC article.
2021
Journal Articles
Griffiths, S.L., Wood, S.J., Fowler, D., Freemantle, N., Hodgekins, J., Jones, P.B., et al. (2021). Improved social functioning following social recovery therapy in first episode psychosis: Do social cognition and neurocognition change following therapy, and do they predict treatment response? Schizophrenia Research 228, 249-255.
Oeztuerk, O.F., Pigoni, A., Wenzel, J., Haas, S.S., Popovic, D., Ruef, A., Dwyer, D.B., Kambeitz-Ilankovic, L., Ruhrmann, S., Chisholm, K., Lalousis, P., Griffiths, S.L., Lichtenstein, T., Rosen, M., Kambeitz, J., Schultze-Lutter, F., Liddle, P., Upthegrove, R., Salokangas, R.K.R., Pantelis, C., Meisenzahl, E., Wood, S.J., Brambilla, P., Borgwardt, S., Falkai, P., Antonucci, L.A., Koutsouleris, N., the, P.C., (2021). The clinical relevance of formal thought disorder in the early stages of psychosis: results from the PRONIA study. European Archives of Psychiatry and Clinical Neuroscience
Perry, BI, Upthegrove, R, Kappelmann, N, Jones, PB, Burgess, S & Khandaker, GM 2021, 'Associations of immunological proteins/traits with schizophrenia, major depression and bipolar disorder: a bi-directional two-sample mendelian randomization study', Brain, Behavior, and Immunity, vol. 97, pp. 176-185.
Husain, MO, Chaudhry, IB, Khan, Z, Khoso, AB, Kiran, T, Bassett, P, Husain, MI, Upthegrove, R & Husain, N 2021, 'Depression and suicidal ideation in schizophrenia spectrum disorder: a cross-sectional study from a lower middle-income country', International Journal of Psychiatry in Clinical Practice, vol. 25, no. 3, pp. 245-251.
Perry, BI, Osimo, E, Mallikarjun, P, Upthegrove, R, Perez, J, Stochl, J, Zammit, S, Howes, O, Jones, P & Khandaker, G 2021, 'Development and external validation of the Psychosis Metabolic Risk Calculator (PsyMetRiC): a cardiometabolic risk prediction algorithm for young people with psychosis', The Lancet Psychiatry.
Leighton, SP, Krishnadas, R, Upthegrove, R, Marwaha, S, Steyerberg, EW, Gkoutos, G, Broome, M, Liddle, P, Everard, L, Singh, S, Freemantle, N, Fowler, D, Jones, P, Sharma, V, Murray, RM, Wykes, T, Drake, R, Buchan, I, Rogers, SN, Cavanagh, J, Lewis, S, Birchwood, M & Mallikarjun, P 2021, 'Development and validation of a non-remission risk prediction model in first episode psychosis: An Analysis of 2 Longitudinal Studies', Schizophrenia Bulletin Open, vol. 2, no. 1, pp. sgab041.
Lalousis, PA, Wood, S, Schmaal, L, Chisholm, K, Griffiths, L, Reniers, R, Bertolino, A, Borgwardt, S, Brambilla, P, Kambeitz, J, Lencer, R, Pantelis, C, Ruhrmann, S, Salokangas, RKR, Schultze-Lutter, F, Bonivento, C, Dwyer, D, Ferro, A, Haidl, T, Rosen, M, Schmidt, A, Meisenzahl, E, Koutsouleris, N, Upthegrove, R & PRONIA Consortium 2021, 'Heterogeneity and classification of recent onset psychosis and depression: a multimodal machine learning approach', Schizophrenia bulletin.
Denno, P, Wallis, S, Caldwell, K, Ives, J, Wood, SJ, Broome, MR, Mallikarjun, P, Oyebode, F & Upthegrove, R 2021, 'Listening to voices: understanding and self-management of auditory verbal hallucinations in young adults', Psychosis.
Perry, BI, Stochl, J, Upthegrove, R, Zammit, S, Wareham, N, Langenberg, C, Winpenny, E, Dunger, DB, Jones, P & Khandaker, GM 2021, 'Longitudinal trends in insulin levels and BMI from childhood and their associations with risks of psychosis and depression in young adults', JAMA psychiatry, vol. 2021, no. 00, pp. 1-10.
Murray, AJ, Rogers, JC, Katshu, MZUH, Liddle, PF & Upthegrove, R 2021, 'Oxidative stress and the pathophysiology and symptom profile of schizophrenia spectrum disorders', Frontiers in Psychiatry, vol. 12, 703452.
Bashir, Z, Griffiths, L & Upthegrove, R 2021, 'Recognition and management of depression in early psychosis', BJPsych Bulletin, pp. 1-7.
Griffiths, SL, Leighton, SP, Mallikarjun, PK, Blake, G, Everard, L, Jones, PB, Fowler, D, Hodgekins, J, Amos, T, Freemantle, N, Sharma, V, Marshall, M, McCrone, P, Singh, SP, Birchwood, M & Upthegrove, R 2021, 'Structure and stability of symptoms in first episode psychosis: a longitudinal network approach', Translational Psychiatry, vol. 11, no. 1, 567.
Corsi-zuelli, F, Deakin, B, De Lima, MHF, Qureshi, O, Barnes, NM, Upthegrove, R, Louzada-junior, P & Del-ben, CM 2021, 'T regulatory cells as a potential therapeutic target in psychosis? Current challenges and future perspectives', Brain, Behaviour, and Immunity Health, vol. 17, 100330.
De Brito, S. A., McDonald, D., Camilleri, J. A., & Rogers, J. C. (2021). Cortical and subcortical gray matter Vol. in psychopathy: A voxel-wise meta-analysis. Journal of Abnormal Psychology, 130(6), 627–640.
Corsi-zuelli, F., Deakin, B., De Lima, M. H. F., Qureshi, O., Barnes, N. M., Upthegrove, R., Louzada-junior, P., & Del-ben, C. M. (2021). T regulatory cells as a potential therapeutic target in psychosis? Current challenges and future perspectives. Brain, Behaviour, and Immunity Health, 17, [100330].
Conen, S., Gregory, C.J., Hinz, R. Smallman,R. Fabiana Corsi-Zuelli, Bill Deakin & Peter S. Talbot. Neuroinflammation as measured by positron emission tomography in patients with recent onset and established schizophrenia: implications for immune pathogenesis. Mol Psychiatry 26, 5398–5406 (2021).
Mothersill D, King S, Holleran L, Dauvermann M, Patlola S, Rokita K, McManus R, Keynon M, McDonald C, Hallahan B, Corvin A, Morris D, Kelly J, McKernan D, Donohoe (2021) Interleukin 6 predicts increased neural response during face processing in a sample of individuals with schizophrenia and healthy participants: A functional magnetic resonance imaging study. Neuroimage Clin. 2021;32:102851. Epub 2021 Oct 7. PMID: 34634589 Free PMC article.
Rokita KI, Dauvermann MR, Mothersill D, Holleran L, Bhatnagar P, McNicholas Á, McKernan D, Morris DW, Kelly J, Hallahan B, McDonald C, Donohoe G.Schizophr Res. (2021) Current psychosocial stress, childhood trauma and cognition in patients with schizophrenia and healthy participants. 237:115-121. Epub 2021 Sep 11.PMID: 34521038
Siegel-Ramsay JE, Romaniuk L, Whalley HC, Roberts N, Branigan H, Stanfield AC, Lawrie SM, Dauvermann MR.Psychiatry Res Neuroimaging (2021) Glutamate and functional connectivity - support for the excitatory-inhibitory imbalance hypothesis in autism spectrum disorders. 313:111302. Epub 2021 May 12.PMID: 34030047
Dauvermann MR, Mothersill D, Rokita KI, King S, Holleran L, Kane R, McKernan DP, Kelly JP, Morris DW, Corvin A, Hallahan B, McDonald C, Donohoe G.Schizophr Bull. (2021) Changes in Default-Mode Network Associated With Childhood Trauma in Schizophrenia. 47(5):1482-1494. PMID: 33823040 Free PMC article.
Smith AJ, Moreno-López L, Davidson E, Dauvermann M, Orellana S, Soneson E, Ioannidis K, Kaser M, van Harmelen AL.BMJ Open. (2021) REACT study protocol: resilience after the COVID-19 threat (REACT) in adolescents. 11(1):e042824. PMID: 33472787 Free PMC article.
Review Article
Barber, L, Reniers, R & Upthegrove, R 2021, 'A review of functional and structural neuroimaging studies to investigate the inner speech model of auditory verbal hallucinations in schizophrenia', Translational Psychiatry, vol. 11, no. 1, 582.
Hett, D., Rogers, J., Humpston, C., & Marwaha, S. (2021). Repetitive transcranial magnetic stimulation (rTMS) for the treatment of depression in adolescence: a systematic review. Journal of Affective Disorders, 278, 460-469.